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It is indeed feasible to replace antibiotics with probiotics, but the key lies in identifying the right probiotic strains that can match the efficacy of the antibiotics they are meant to substitute. Alongside this, robust scientific and technical support is essential to ensure effective application solutions that stabilize the performance of probiotics.
According to Xinmuwang, on December 29, it was reported that the use of sub-therapeutic doses of antibiotics in animal feed has long been seen as beneficial for improving animal performance. However, the long-term use of such practices has sparked increasing controversy.
Currently, antibiotic resistance is becoming a more pressing issue, and the cost of using antibiotics is rising. With growing public concern and stricter national regulations, the use of antibiotics in feed is being reduced. This shift presents an urgent need for the livestock and poultry industry, prompting increased interest in probiotics for maintaining gut health.
Despite this, in practical applications, probiotics have not consistently delivered the expected benefits in managing intestinal health. As a result, many in the industry remain skeptical about their ability to fully replace antibiotics. The main challenges lie in two areas.
First, the effectiveness of probiotics is often not as strong as that of antibiotics. Probiotic systems are complex, and different strains exhibit varying characteristics and functions. Even within the same strain, results can differ significantly depending on the environment and application method. Although the Ministry of Agriculture has approved over 30 species of feed microorganisms, the market is flooded with numerous products from hundreds of companies, making it difficult to distinguish quality. Without proper evaluation methods, many probiotics end up functioning like placebos.
Second, the stability of probiotics remains an issue. Their performance depends on the strain’s ability to survive harsh conditions, such as high temperatures during feed processing, acidic environments in the gut, and exposure to bile salts. These factors make it challenging to ensure consistent results. Additionally, the use of probiotics must be carefully integrated with other treatments, such as antibiotics or acidifiers. Without proper compatibility testing, improper combinations can reduce the overall effectiveness of the treatment.
So, can a probiotic program effectively reduce antibiotic dependence? The answer lies in selecting the right probiotic through systematic evaluation. First, the probiotics must demonstrate clear and measurable effects—ideally comparable to antibiotics. This can be achieved through laboratory tests that compare the antibacterial activity of different probiotic strains against harmful bacteria.
Second, a customized and well-designed application program is essential to ensure stable performance. Testing the survival rate of probiotics after high-temperature processing, under acidic conditions, and in simulated bile salt environments helps identify the most resilient strains. In practice, integrating probiotics into existing management programs requires careful compatibility testing with other additives to optimize results.
In conclusion, replacing antibiotics with probiotics is not only possible but necessary. The key is to choose the right strains and provide scientific support to ensure their effectiveness. Professional lab testing and tailored evaluation systems are critical for successful implementation.
Proper selection of probiotics can help reduce antibiotic use in a responsible and informed way. Scientific assessment and strategic planning will guide the industry toward a more sustainable future.
It's worth noting that probiotics are biological preparations made by fermenting, purifying, and drying beneficial microorganisms from the animal gut, approved by the Ministry of Agriculture. They are considered ideal green alternatives for reducing or replacing antibiotics.
**Tips for Using Prebiotics:**
1. Start feeding probiotics to broilers at 3 days old, and to pigs at around 15 days.
2. When using antibiotics, limit their use to once a week after starting probiotics. If antibiotics are needed, stop probiotics during treatment.
3. Before adding probiotics to drinking water, disinfect the water one or two days in advance, or add probiotics before the animals drink.
4. Avoid mixing probiotics with feeds containing antibiotics, as this may reduce their effectiveness.
5. Use the product as soon as possible after opening the package to maintain potency.
Quick-solving enzymes can enhance the effect of probiotics by creating an anaerobic environment in the gut, which supports the growth of beneficial bacteria. According to reports, this combination can double the effectiveness of probiotics.
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