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It is feasible to replace antibiotics with probiotics, provided that the right strains are selected to achieve similar efficacy. The key lies in identifying probiotic strains that can match or closely mimic the effects of antibiotics. In addition, scientific and technical support is essential to develop application solutions that ensure consistent and reliable performance of probiotics.
Xinmuwang reported on December 29 that the use of sub-therapeutic levels of antibiotics in livestock and poultry feed has been beneficial for improving animal performance, but long-term usage remains controversial. As public concern over antibiotic use increases, regulations have become stricter, leading to a decline in their application. This shift presents an urgent need for alternatives in the feed industry, and interest in probiotics for maintaining gut health in animals is growing rapidly.
However, in practice, probiotics often fail to deliver the expected results in managing intestinal health. This has led to skepticism about their ability to replace antibiotics. The main challenges lie in two areas: first, the effectiveness of probiotics is not always comparable to that of antibiotics; second, the stability of probiotics during application remains inconsistent.
The probiotic system is highly complex, with different strains exhibiting varying characteristics based on their origin and function. Even within the same strain, there can be significant differences in performance. With over 30 approved microbial species by the Ministry of Agriculture and hundreds of products on the market, the quality and effectiveness of these products vary widely. Without proper evaluation methods, many probiotics are used as placebos, failing to deliver real benefits.
Another major issue is the instability of probiotics during processing and storage. Factors such as high-temperature granulation, acid resistance, and bile salt tolerance significantly affect their survival and activity. Without systematic testing, it's easy to choose the wrong strain, leading to poor results. Moreover, intestinal health management typically involves multiple strategies, and probiotics must be compatible with other additives like antibiotics or acidifiers. A lack of comprehensive compatibility testing can lead to ineffective combinations and reduced overall performance.
To effectively reduce antibiotic dependence, the key is to select a well-evaluated probiotic program. First, the probiotic must demonstrate clear and measurable effects, ideally matching or approaching the antibacterial properties of antibiotics. This can be confirmed through laboratory tests comparing the inhibition of harmful bacteria between probiotics and antibiotics. Second, a customized application plan is needed to ensure stability under various conditions, such as feed processing and digestive environments. Testing the survival rate of probiotics after granulation, in acidic conditions, and in simulated bile salt environments helps identify the most resilient strains.
In practical applications, intestinal health requires a comprehensive approach. Before using probiotics, it's important to understand their compatibility with other feed additives. Through professional compatibility testing, producers can determine how probiotics interact with antibiotics, coccidiostats, and acidifiers, allowing for more effective and tailored formulations.
In conclusion, replacing antibiotics with probiotics is not only possible but increasingly necessary. The success depends on selecting the right strains and ensuring they perform reliably through scientific evaluation and customized application strategies. With proper guidance and testing, probiotics can play a vital role in reducing antibiotic use while promoting healthier livestock.
Additionally, when using probiotics, certain precautions should be taken:
1. Start feeding probiotics to broilers from day 3 and to pigs from around 15 days old.
2. When using antibiotics, limit their use to once a week after starting probiotics, and discontinue probiotics when antibiotics are administered.
3. If adding probiotics to drinking water, disinfect the water a day or two in advance, and reduce the amount of disinfectant or add probiotics before providing water.
4. Avoid mixing probiotics with feeds containing antibiotics, as this can reduce their effectiveness.
5. Use the product as soon as possible after opening to maintain potency.
Quick-solving enzymes can enhance the effectiveness of probiotics by creating an anaerobic environment in the gut, which supports the growth of beneficial bacteria. According to reports, this combination can significantly improve gut health and performance in animals.
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